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pentobarbital will lessen the level or impact of ripretinib by affecting hepatic/intestinal enzyme CYP3A4 metabolism.pentobarbital will lower the extent or influence of budesonide by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Use Warning/Monitor.Use Warning/Observe. CYP3A4 inducers may improve the metabolism of clopidogrel to its Lively